What are NITYR® (nitisinone) Tablets?

NITYR® (nitisinone) Tablets are a competitive inhibitor of 4-hydroxyphenyl-pyruvate dioxygenase indicated for the treatment of adult and pediatric patients with hereditary tyrosinemia type 1 (HT-1) in combination with dietary restriction of tyrosine and phenylalanine.

Why choose NITYR?Enroll your patients


Designed for convenience, NITYR gives patients and their caregivers one less thing to worry about. NITYR liberates patients from the start, with the convenience, flexibility and freedom that has enabled 100% of the patients who have transitioned to NITYR to not voluntarily return to Orfadin®* (nitisinone).1

  • Very small and discreet2
  • Baby aspirin-sized: 20% the volume of a single Orfadin* (nitisinone) capsule2
  • NITYR is suitable for all age groups. It can be given as a suspension, crushed and mixed with applesauce, or swallowed whole
  • No refrigeration restrictions
  • Can be taken with or without food3
  • Makes NITYR easy to take on the go
  • Bioequivalent to Orfadin* (nitisinone) capsules4
  • Same efficacy, same safety and same side effects as Orfadin*4
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We know that life-changing treatments need a support system which is tailored to the unique challenges you might be facing. That’s why we created Cycle Vita, our dedicated hub support program, which delivers individualized product support** at every step. Including:

  • Financial Assistance
  • Patient Nutrition Program
  • Quick Start Program
Find out more
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A friendly, familiar team is waiting here at Cycle Vita, for you, at every step.

+1 (888) 360-8482

* Orfadin is a registered trademark, licensed by Swedish Orphan Biovitrum AB (publ) and is marketed by Sobi, Inc.

** Some areas of support may not be accessible to all patients. Eligibility criteria may apply to ensure compliance with all applicable federal and state requirements, and benefits may be limited to commercially insured patients only. For more detailed information about eligibility, terms and conditions, please contact the Cycle Vita team at +1 (888) 360-8482.


1. Data on file: REF-00005. Data represents fully enrolled, insured NITYR patients in the US from August 2017 to February 2021.
2. Data on file: REF-00041.
3. NITYR (Nitisinone) Tablets. Prescribing Information. Cycle Pharmaceuticals Ltd.
4. Data on file: REF-00047.